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Healthcare online Keeping you up-to-date
VOL.  6     ISSUE:  11    November 27, 2008 Medical Services Department

SQUARE Pharmaceuticals Ltd.

Features

EDITORIAL TEAM

OMAR AKRAMUR RAB

MBBS, FCGP, FIAGP,

P G Dip. Business Management

MAHFUZUR RAHMAN, MBBS

 

EDITORIAL

Dear Doctor,

Welcome to this edition of 'e-SQUARE'. Hope you are enjoying this online healthcare bulletin.

Our current issue focused on some interesting features like -

"New Screening !", "A New Biomarker !", "Potassium Alert !",

       "Caffeine Risk !",  "Fish Cuts Risk !", "New Imaging !".

In our regular feature, we have some new products information of SQUARE Pharmaceuticals Ltd. as well.

We will appreciate your feedback !

Click on to reply mode.

Yours sincerely,

 

Editorial Team

Reply Mode      : e-square@squaregroup.com

The views expressed in this publication do not necessarily reflect those of its editor or SQUARE Pharmaceuticals Ltd.

 New Screening !

New And Enhanced Breast Screening

Many women find conventional mammography uncomfortable, and doctors admit the technology misses some breast cancers, especially in younger women with denser breasts. What’s more, the test exposes women to radiation. New technology being developed at the University of Bristol in the United Kingdom may be the answer. Researchers there are working on an imaging technique that uses radio waves, similar to radar systems used in the aviation and other industries, to identify breast problems. The study author said that this new imaging technique works by transmitting radio waves of a very low energy and detecting reflected signals; it then uses these signals to make a 3D image of the breast. This is basically the same as any radar system, such as the radars used for air traffic control at the airports, the researcher added. For the test, women place their breast in a ceramic cup where transmitters view it from several different angles. So far the investigators have tested the device in about 60 women, finding it takes about six minutes to examine both breasts. The researchers will now conduct a study comparing mammograms with the new test to see if the new test picks up as many breast cancers.

SOURCE: Ivanhoe Newswire, November 2008

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 A New Biomarker !

 New Marker For Heart Failure

A new biomarker may help identify people at greatest risk for heart failure. According to researchers who discovered the marker known as resisten, the risk of developing heart failure rose 38 percent for every 10 nanograms per milliliter increase in blood levels. The study author from Emory University School of Medicine quoted that this is one of the strongest predictors of new-onset heart failure they have been able to find, and it holds up even when people control for other biomarkers and risk factors including high blood pressure and diabetes. The researchers uncovered the marker by using data collected in a study conducted among 3,000 older people who were followed for seven years. The investigators believe resistin may be most useful in identifying heart failure risk in people already considered at high risk for the condition.  “Considering the increasing number of people who are obese or have diabetes, very many of them are going to be at some level of risk for heart failure later in life,” said the researcher. “The value of a marker such as resistin may be in accurately identifying among this large population of at-risk individuals who is at the highest risk and then targeting interventions to those people”, he added.

SOURCE: Ivanhoe Newswire, November 2008

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 Potassium Alert !

Low Potassium Leads To High Blood Pressure

Getting enough potassium may be even more important than lowering sodium for maintaining a healthy blood pressure -- especially for African Americans. “There has been a lot of publicity about lowering salt or sodium in the diet in order to lower blood pressure, but not enough on increasing dietary potassium,” the study’s lead author of the University of Texas Southwestern Medical Center in Dallas, Texas, was quoted as saying. Researchers analyzed data from 3,300 subjects from the Dallas Heart Study, about half of whom were African American. The results showed the amount of potassium in urine samples was strongly related to blood pressure. The lower the levels of potassium in the urine, the higher the blood pressure.  The relationship between low potassium and high blood pressure remained significant even when other risk factors like age, race, high cholesterol, diabetes and smoking were taken into account.

SOURCE: Ivanhoe Newswire, November 2008

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 Caffeine Risk !

Caffeine In Pregnancy Linked With Low Birth Weight Risk

Even consuming low amounts of caffeine during pregnancy may increase the risk of having a low birth weight baby, new research shows. British researchers studied 2,645 pregnant women, average age 30, with low-risk pregnancies. Their average caffeine intake during pregnancy was 159 milligrams a day, much lower than the 300 mg/day recommended by the U.K.'s Food Standards Agency. Tea was the main source of caffeine (62 percent), followed by coffee (14 percent), cola (12 percent), chocolate (8 percent), and soft drinks (2 percent). Most of the women's babies were born at full term with an average birth weight of 3,450 grams (around the U.K. average), while 4 percent of the babies were born prematurely, 0.3 percent were stillborn, and 0.7 percent were miscarried late. The researchers at the University of Leicester and the University of Leeds concluded that higher caffeine intake was associated with increased risk of low birth weight. Compared to women who consumed less than 100 mg/day of caffeine (equivalent of less than one cup of coffee), the risk of having a lower birth weight baby increased by 20 percent for women who had 100-199 mg/day, by 50 percent for those who consumed 200-299 mg/day, and by 40 percent for over 300 mg/day. Caffeine consumption of more than 100 mg/day was associated with a fetal weight reduction of 34-59 grams in the first trimester, 24-74g in the second trimester, and 66-89g in the third trimester. The effect was significant and consistent across all trimesters with caffeine consumption of more than 200 mg/day. The link between caffeine and low birth weight was strongest in women who metabolized caffeine more quickly. Pregnant women should significantly reduce their caffeine consumption before and during pregnancy, the researchers said. They did agree that pregnant women should reduce their caffeine consumption, but must not replace it with unhealthy alternatives such as alcoholic drinks or soft drinks full of sugar.

SOURCE: HealthDay News, November 2008

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 Fish Cuts Risk !

Fish Twice A Week Reduces Diabetics' Kidney Risks

Eating fish twice a week may help reduce the risk of kidney disease in people with diabetes, according to a British study of more than 22,000 adults, including 517 with diabetes. The participants' fish consumption was determined using dietary and lifestyle questionnaires. People with diabetes who ate less than one serving of fish per week were about four times more likely (18 percent) to have protein in their urine than those who ate at least two servings of fish per week (4 percent). "Protein in the urine is one of the earliest signs of kidney disease," noted study co-author of the Medical Research Council epidemiology unit at Addenbrooke's Hospital, Cambridge. The researchers suggested that the "unique nutrient composition of fish" may benefit kidney function by enhancing blood glucose control and improving plasma lipid profiles. People who consume fish may have other lifestyle factors that reduce their risk of having albuminuria, but the study design attempted to account for that possibility, the expert added. In addition to eating fish, other measures that help lower the risk of albuminuria include tight control of glucose, keeping blood pressure under control, quitting smoking, and following a diabetic diet as prescribed by a doctor, according to the kidney foundation.

SOURCE: HealthDay News, November 2008

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 New Imaging !

New Imaging Recognizes Types Of Liver Disease

A new imaging technology called magnetic resonance elastography (MRE) is highly accurate in identifying liver diseases and can help eliminate the need for liver biopsies, according to Mayo Clinic researchers. MRE, which was developed at the Mayo Clinic, produces color-coded images (elastograms) that indicate how internal organs, muscles and tissues would feel to the touch. Purple is the softest, and red is the stiffest. "Knowing the liver's elasticity or stiffness is invaluable in diagnosing liver disease. A healthy liver is very soft, while a liver with early disease begins to stiffen. A liver with cirrhosis, advanced liver disease, can be rock hard," said the experts in a Mayo news release. In this study, the researchers used MRE to check 113 patients, aged 19 to 78, who had a wide variety of liver diseases and had undergone a liver biopsy within the previous year. "Results showed that elastography was highly accurate in detecting moderate-to-severe hepatic fibrosis even with the variety in age, types of liver disease, and body size," the researcher said. The study found that MRE was 88 percent accurate in detecting cirrhosis and 97 percent accurate in identifying nonalcoholic fatty liver disease with no significant inflammation or fibrosis. "Using MRE, we can confidently avoid liver biopsies for patients with no evidence of advanced fibrosis, as well as for patients with cirrhosis," the scientist added.

SOURCE: HealthDay News, November 2008

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New Products of SQUARE Pharmaceuticals Ltd.

  Product Nectar® Linctus
  Generic Name Glycerol BP + Liquid Sugar Pharma Grade
  Strength

(0.75 + 1.93 ml)/5 ml

  Dosage form Linctus
  Therapeutic Category Other cough and cold preparations
  Product De-rash®
Generic Name

Zinc Oxide

Strength 40%
Dosage form Ointment
Therapeutic Category Emollient and protectant
  Product Clofenac® 100 TR
  Generic Name Diclofenac Sodium
  Strength 100 mg
  Dosage form Timed release capsule
  Therapeutic Category Antirheumatic non steroid

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