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Healthcare online Keeping you up-to-date
VOL.  7     ISSUE:  9    2009 Medical Services Department

SQUARE Pharmaceuticals Ltd.

Features

EDITORIAL TEAM

OMAR AKRAMUR RAB

MBBS, FCGP, FIAGP,

P G Dip. Business Management

MAHFUZUR RAHMAN, MBBS

 

EDITORIAL

Dear Doctor,

Welcome to this edition of 'e-SQUARE'. We hope you are enjoying this online healthcare bulletin.

Our current issue focused on some interesting features like -

"Diabetic Kidney Alert !", "Drug Helps Colitis !", ""Silent" Heart

 Disease !", "Exercise And Ca Prostate !",  "Faster TB Detection !", "Depression And Bone Loss !".

In our regular feature, we have some products information of SQUARE Pharmaceuticals Ltd. as well.

We will appreciate your feedback !

Click on to reply mode.

Yours sincerely,

 

Editorial Team

Reply Mode      : e-square@squaregroup.com

The views expressed in this publication do not necessarily reflect those of its editor or SQUARE Pharmaceuticals Ltd.

 Diabetic Kidney Alert !

   Cells Predict Diabetic Kidney Disease In Men

A key indicator for diabetic kidney disease in men may be traced to a cell type linked to allergic inflammation. More and more allergy patients are being diagnosed across the world, and kidney disease is a severe complication for diabetics. Finding a relationship between the two shows great promise for the development of new preventive drugs, according to researchers. The researchers examined 800 type 2 diabetics for two factors, eosinophil count and albumin excretion. Eosinophils contribute to inflammation in allergic diseases. Urine albumin is a strong indicator of diabetic kidney disease. The study showed the higher the eosinophil count, the higher the albumin excretion rate, and the higher the risk for diabetic kidney disease. The relationship between the markers for allergies and kidney disease was even stronger than that for the known risks factors of blood pressure and poor diabetes control. These results were strong in male patients, but no correlation was found in the women participants. Kidney disease is a major risk factor for heart disease in type 2 diabetics. If previous studies correlating allergies and asthma to heart disease are correct, eosinophil count may be very useful in predicting related both diabetes-related kidney disease and heart disease in men.  

SOURCE: Ivanhoe Newswire, October 2009

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 Drug Helps Colitis !

Drug May Help Colitis Patients Avoid Surgery

Treatment with the drug infliximab reduced the need for surgery in ulcerative colitis patients by almost half, a new study found. Ulcerative colitis causes chronic inflammation of the colon and often leads to surgical removal of the colon (colectomy). This study included 728 patients who received either an inactive placebo or infliximab for 46 weeks. After one year of follow-up, the researchers found that "treatment with infliximab reduced the need for colectomy by 41 percent compared to patients treated with placebo,"according to the  lead author and Mayo Clinic gastroenterologist. "One of the most feared outcomes for ulcerative colitis patients is surgical removal of the colon. Our research hopes to provide other treatment solutions for patients beyond surgery," the researcher said.

SOURCE:  HealthDay News, October 2009

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 “Silent” Heart Disease !

 Simple Test Might Detect 'Silent' Heart Disease

A simple test that detects blockages in coronary arteries may help doctors identify patients with "silent" heart disease without requiring major new medical expenses. The tests -- coronary artery calcium scans -- pinpoint clogs in coronary arteries caused by plaque. They can warn doctors that certain patients are at risk of developing heart disease. Still, "over half of patients who suffer heart attacks have no warning that they have heart disease until the heart attack occurs. If we knew the patients were at risk, current treatments could prevent the majority of these unnecessary events," according to the chief of cardiac imaging at the S. Mark Taper Foundation Imaging Center of Cedars-Sinai Heart Institute, Los Angeles. "We had to address the concerns about unnecessary testing and costs related to this potentially lifesaving procedure," he said. In the new study, researchers performed the scan on 1,361 volunteers who were at intermediate risk of heart disease (neither high nor low risk) and followed them for four years. High scores, indicating more plaque, were linked to higher risk of heart problems. Those with low scores, however, got fewer tests and the costs were lower, suggesting the tests won't lead to hugely expensive tests in the general population of those who are screened. Heart disease is the top cause of death in the United States, killing an estimated 652,091 people each year, according to the U.S. Centers for Disease Control and Prevention.

SOURCE: HealthDay News, October 2009

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 Exercise And Ca Prostate !

Exercise May Prevent Prostate Cancer

Regular exercise may help protect men from prostate cancer, says a new study. U.S. researchers looked at 190 men who had a prostate biopsy and found that those who were moderately active -- anything equivalent to walking at a moderate pace for several hours a week -- were significantly less likely to be diagnosed with prostate cancer. The study also found that exercise was associated with less aggressive disease in men who did develop prostate cancer. "As the amount of exercise increased, the risk of cancer decreased," lead author at Duke University Medical Center. The majority (58 percent) of the men in this study were sedentary, which means they exercised less than the equivalent of one hour per week of easy walking.

SOURCE: HealthDay News, September 2009

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 Faster TB Detection !

Faster Detection Of TB May Be On The Horizon

A new test can rapidly identify active tuberculosis in people who've had negative sputum tests, say European researchers. In about half of all people with active TB, the disease-causing bacterium can't be identified using sputum tests. Because of this, new diagnostic tests are needed to help control the spread of TB, the researchers said. "In this study, we showed that a differentiation between active pulmonary tuberculosis and [latent TB infection] is possible by the ELISpot test," according to the principal investigator of the Tuberculosis Network European Trials group study. The study included 347 people, including 71 with active pulmonary TB. In the 71, ELISpot results were positive in 65 cases (91.5 percent). An ELISpot test detects active TB by comparing the frequencies of TB-specific T-lymphocytes in the blood with those in the lung, with results in a day. The findings show that a positive ELISpot test result is highly indicative of active TB, whereas a negative result almost excludes active TB, the researcher added. About one-third of the world's population is infected with the bacterium that causes TB, M. tuberculosis, but only 10 to 20 percent of those who are infected will develop active TB, according to the World Health Organization. Active TB is the seventh-leading cause of death worldwide. 

SOURCE: HealthDay News, September 2009

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 Depression And Bone Loss !

Depression Hard On The Bones

People who suffer from major depression are at risk for low bone mineral density (BMD), research hints. In the last 14 years, "ample research" has implicated major depression in bone loss and the bone-thinning disease osteoporosis, according to the researchers from The Hebrew University of Jerusalem in Israel. To investigate further, the investigators pooled data from 23 studies involving 2327 depressed and 21,141 non-depressed adults. Overall, depressed individuals had less dense bones than non-depressed individuals, they found. Depressed individuals also had increased levels of bone resorption markers. Based on these findings and prior studies, "We propose that all individuals psychiatrically diagnosed with major depression are at risk for developing osteoporosis, with depressed women -- particularly those who are premenopausal -- showing a higher risk than men," the scientists conclude. People with major depression should have their BMD checked periodically, they conclude.

SOURCE: Reuters Health, September 2009

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Products of SQUARE Pharmaceuticals Ltd.

  Product Evit® 200 Licap
  Generic Name Vitamin E
  Strength 200 mg 
  Dosage form Licap
  Therapeutic Category Vitamin E Plain
  Product K-One® MM
Generic Name

Phytomenadione

Strength

2 mg/0.2 ml

Dosage form Solution/Injection
Therapeutic Category Vitamin K
  Product Flugal® 200 Capsule
  Generic Name Fluconazole USP
  Strength

200 mg

  Dosage form Capsule
  Therapeutic Category Systemic Antifungal

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