Features

Scarless Surgery !

Soy Fight  Cancer !

Traffic, Dust Alert  !

Higher Dose Better !

Depression After Surgery !

Optical Technology !

 Products of SQUARE Pharmaceuticals Ltd.

EDITORIAL TEAM

OMAR AKRAMUR RAB

MBBS, FCGP, FIAGP,

P G Dip. Business Management

MAHFUZUR RAHMAN, MBBS

EDITORIAL

Dear Doctor,

 Hope you are enjoying 'e-SQUARE' online healthcare bulletin.

Our current issue focused on some interesting features like -

"Scarless Surgery !", "Soy Fight Cancer !", "Traffic, Dust Alert !", "Higher Dose Better !",  "Depression After Surgery !", "Optical Technology !".

In our regular feature, we have some products information of SQUARE Pharmaceuticals Ltd. as well.

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Yours sincerely,

Editorial Team

Reply Mode      : e-square@squaregroup.com

The views expressed in this publication do not necessarily reflect those of its editor or SQUARE Pharmaceuticals Ltd.

Traffic, Dust Linked To Asthma In Kids

Infants exposed to outdoor traffic pollution and indoor endotoxin are at increased risk for asthma, researchers say. Endotoxin -- a component of bacteria believed to trigger an immune response in humans -- is found in dust. University of Cincinnati College of Medicine researchers found persistent wheezing (an early warning sign of asthma and other lung conditions) in 36 percent of 3-year-olds who were exposed to high levels of traffic pollution and indoor endotoxin as infants. In comparison, wheezing was seen in 11 percent of children exposed to low levels of outdoor and indoor allergens as infants, and in 18 percent of children exposed to high levels of traffic pollution and low levels of indoor endotoxin. Endotoxin exposure alone appeared to have little effect on children, the study authors noted. "There is a clear synergistic effect from co-exposure to traffic-related particles and endotoxin above and beyond what you would see with a single exposure that can be connected to persistent wheezing by age 3," according to a research assistant professor of environmental health. "These two exposure sources -- when simultaneously present at high levels -- appear to work together to negatively impact the health of young children with developing lungs." "Traffic-related particles and endotoxin both seem to trigger an inflammatory response in the children monitored in this study. When put together, that effect is amplified to have a greater impact on the body's response," the scientist explained. "The earlier in life this type of exposure occurs, the more impact it may have long term. Lung development occurs in children up through age 18 or 20. Exposure earlier in life to both endotoxin and traffic will have a greater impact on developing lungs compared to adults whose lungs are already developed."

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Treating Depression After Surgery Speeds Recovery

A simple telephone intervention improved mood, physical functioning, and overall quality of life in patients who were depressed after heart bypass surgery, researchers reported in a late breaking clinical trial at the American Heart Association Scientific Sessions 2009. In the so-called Bypassing the Blues trial, 50 percent of patients who were depressed after having coronary artery bypass surgery saw improvements of at least 50 percent in their negative mood after participating in the intervention, compared with 29 percent of control patients who received usual care. Depressed men benefited most and were far less likely to be re-hospitalized for heart-related causes than men who got usual care, according to the researcher from the University of Pittsburgh, Pennsylvania. Depression after heart surgery "is often unrecognized," the scientist noted. When a patient still has symptoms, such as pain, the physician will order another stress test or other heart test "and they overlook the obvious sometimes. In the trial, researchers screened heart bypass patients for depression before they were discharged from the hospital. Screen-positive patients were contacted again two weeks later when they were at home to see if their depression was persisting. If so, they were randomly allocated to receive an 8-month course of telephone-delivered collaborative care or usual care.Patients in the collaborative care group received a workbook, mailed to them at home, which contained basic "talk therapy" approaches as well as recommendations for exercising, getting plenty of quality sleep, and staying connected socially. Antidepressants were provided if patients felt it necessary. Patients who were already taking antidepressants could have their dose changed or could switch to another medication, and suggestions were made for consults with local mental health specialists if patients were not improving, the researcher said. Trained nurse practitioners phoned the patients every other week at the start of the intervention and then once a month as the study progressed. This simple intervention proved effective in relieving depression after heart bypass surgery, the researcher reported. Patients should be screened for depression after heart bypass surgery, he said, because it occurs in roughly 25 percent of cases, and, as this study shows, treating depression speeds recovery..  

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 New Polyp Detection Method Could Be Cost-Saver

Optical technology could help physicians detect small colorectal polyps during colonoscopies and save money, too, new research suggests. Colorectal cancer is the second-leading cause of death from cancer, outranked only by lung cancer. It will kill an estimated 49,920 people in the United States this year, according to the American Cancer Society. But early detection, which allows doctors to remove pre-cancerous polyps, can prevent deaths.  In the study, British researchers examined the records of the diagnosis of 363 small colorectal polyps that were found in 130 people. Their aim was to determine if optical diagnosis was accurate.  They found that optical technology allowed colonoscopists to accurately pinpoint up to 93 percent of small colorectal polyps. This is about the same level as histopathology. The researchers estimated that using optical diagnosis for the people in the study would have saved $22,000 in medical costs. By some estimates, use of optical technology instead of histopathology could save $95 million a year in the United States. "Optical diagnosis for small colonic polyps could become acceptable standard of care in routine non-academic clinical practice," the study authors concluded.

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Perindopril Erbumine BP

4 mg

200 mg

200 mg/5 ml