Hyponor^™ injection

Indication:
For blood pressure control in certain acute hypotensive states (e.g. pheochromocytomectomy, sympathectomy, poliomyelitis, spinal anesthesia, myocardial infarction, septicemia, blood transfusion, and drug reactions). As an adjunct in the treatment of cardiac arrest and profound hypotension.

Dosage & Administration:
Upper gastrointestinal haemorrhage:
Adult: Intraperitoneal admin: 8 mg in 250 ml of 0.9% sodium chloride inj. alternatively, instill 8 mg in 100 ml of 0.9% sodium chloride solution through a nasogastric tube every hr for 6–8 hr, then every 2 hr for 4–6 hr. Withdraw drug gradually.

Acute hypotensive states:
Adult: Initially, 8-12 mcg/minute, up to 8-30 mcg/minute in refractory shock. Infuse using a solution of 4 mcg/ml in glucose 5%, or sodium chloride 0.9% and glucose 5% at a rate of 2-3 ml/minute. Adjust according to BP response. Average maintenance dose: 0.5-1 ml/minute (2-4 mcg/minute). Infuse via a central venous catheter or into a large vein. Child: Administer at a rate of 2 mcg/minute. Adjust rate according to BP response and perfusion. Elderly: Initial dose should be at low end of dose range.

Preparation:
Hyponor^™: Each box contains 1 Ampoule in a blister pack.